Multidomain Synthetic Peptide B2A2 Synergistically Enhances BMP-2 In Vitro
نویسندگان
چکیده
منابع مشابه
Multidomain synthetic peptide B2A2 synergistically enhances BMP-2 in vitro.
UNLABELLED A multidomain, synthetic peptide designated B2A2 synergizes the activity of BMP-2. B2A2 interacts with BMP receptor isoforms, potentiating the action of BMP-2 in activating alkaline phosphatase and triggering Smad and MAPK signaling. B2A2's design permits its delivery as a local surface coating as well as a soluble co-factor, thus broadening potential bioengineering applications. I...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2004
ISSN: 0884-0431
DOI: 10.1359/jbmr.041104